POLYCYSTIC OVARIAN SYNDROME (PCOS)

What is polycystic ovary syndrome?

Polycystic (literally, many cysts) ovary syndrome (PCOS or PCO) is a complex condition that affects the ovaries (the organs in a woman's body that produce eggs).

In PCOS, the ovaries are bigger than average, and the outer surface of the ovary has an abnormally large number of small follicles (the sac of fluid that grows around the egg under the influence of stimulating hormones from the brain).

In PCOS, these follicles remain immature, never growing to full development or ovulating to produce an egg capable of being fertilised. For the woman this means that she rarely ovulates (releases an egg) and so is less fertile. In addition, she does not have regular periods and may go for many weeks without a period. Other features of the condition are excess weight and excess body hair.

The condition is relatively common among infertile women and particularly common among women with ovulation problems (an incidence of about 75 per cent). In the general population, around 25 per cent of women will have polycystic ovaries seen on ultrasound examination but most have no other symptoms or signs of PCOS and are perfectly healthy. The ultrasound appearance is also found in up to 14 per cent of women on the contraceptive pill.

What are the symptoms of polycystic ovary syndrome (PCOS)?

Not all women with PCOS share the same symptoms. These are some of the symptoms of PCOS:

Causes of PCOS

PCOS develops when the ovaries overproduce androgens (e.g., testosterone) which are normally produced in the ovary. Androgen overproduction often results from overproduction of LH (luteinizing hormone), which is produced by the pituitary gland, a small organ at the base of the brain that controls the ovary.

Insulin is a hormone that controls blood sugar. Research also suggests that when insulin levels in the blood are high enough, the ovary can be stimulated to produce more testosterone. The combination of ovaries that are responsive to insulin and high insulin levels in the blood, can result in the overproduction of testosterone.

Many women are “insulin resistant”, a condition where blood sugar can only be controlled by producing more insulin than normal. Being overweight, which itself can cause insulin levels to rise, may intensify PCOS, but not all women who are overweight develop PCOS.

Polycystic ovary syndrome PCOS Treatment Cure

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